There is a big difference between enteric coated capsules and gastric capsules. First of all, enteric coated capsules can resist gastric acid, but can not resist the digestive juice mixed in the intestine. Therefore, enteric coated capsules will dissolve in the intestines, while gastric coated capsules are not acid resistant, so they will dissolve in the stomach.
Gastric coated capsules usually dissolve within half an hour, while enteric coated capsules usually dissolve after 2 hours, because it takes 2 hours for the human stomach to empty.
The plant enteric coated capsule avoids the risks related to animal protein, ensures the green safety of the capsule, and provides a new way for the enteric coating of special drugs (easy to cross link with proteins and have therapeutic reactions). It has expanded the scope of capsules in the pharmaceutical field, provided a more convenient, fast, safe and effective solution for the management of special drugs, and made it possible for pharmaceutical enterprises to produce special types of enteric soluble drugs in a rapid, mass and low-cost manner.
raw material:
Stomach soluble coating materials include hydroxypropyl methylcellulose (HPMC), hydroxypropyl cellulose (HPC), type IV acrylic resin, polyvinylpyrrolidone (PVP) and polyvinyl acetal diethylaminoacetic acid (AEA).
Enteric coating materials include shellac, cellulose phthalate acetate (CAP), acrylic resin (I, II, III) and hydroxypropyl methylcellulose phthalate (HPMCP).
